Interactor 1: TNR5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
Gene: CD40

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 20614026
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0023035 - CD40 signaling pathway
GO:0031625 - ubiquitin protein ligase binding
GO:0035631 - CD40 receptor complex
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 277
Hs

1 1072
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024