HitPredict

Interactor 1: TNR5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
Gene: CD40

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12150997
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 277 Hs			1 693
+	Hs
		1348540 TNR11_HUMAN (22-219): 4.69e-56: 192: 36.87		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		584486 TNR1A_HUMAN (23-251): 1.84e-39: 144: 20.59		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Mm
		626876 TNR1A_MOUSE (23-249): 2.31e-41: 149: 22.27		TAB2_MOUSE (1-693): 7.87e-108: 344: 94.66
+	Hs
		154304 TR10B_HUMAN (13-273): 6.41e-48: 166: 17.90		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		554265 TNR1A_HUMAN (23-251): 1.84e-39: 144: 20.59		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		257648 FRAS1_HUMAN (24-194): 6.45e-21: 94.6: 19.49		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54