HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25636800
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 540
+	Hs
		310066 TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		1190089 TNKS2_HUMAN (187-313): 3.7e-30: 122: 17.97		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Mm
		57587 ANKR1_MOUSE (12-280): 1.61e-64: 207: 26.20		TITIN_MOUSE (92-539): 1.35e-11: 69.8: 12.53
+	Hs
		883550 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1192213 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Mm
		103609 ANK3_MOUSE (1-130): 6.93e-29: 118: 10.77		MICA3_MOUSE (76-508): 9.17e-24: 108: 13.48
+	Hs
		1021422 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Hs
		310053 TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		1056981 TNKS2_HUMAN (187-313): 3.7e-30: 122: 17.97		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		1336188 KDIS_HUMAN (225-314): 1.26e-20: 94.5: 13.33		MAGE1_HUMAN (183-537): 6.13e-11: 67.2: 9.58