HitPredict

Interactor 1: PTX3 (P26022)
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)
Gene: PTX3

Interactor 2: FGF8 (P55075)
Fibroblast growth factor 8 (FGF-8) (Androgen-induced growth factor) (AIGF) (Heparin-binding growth factor 8) (HBGF-8)
Gene: FGF8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25912421
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 233
+	Hs
		283338 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF18_HUMAN (53-232): 1.09e-65: 203: 54.44
+	Hs
		640030 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF20_HUMAN (28-204): 4.91e-64: 199: 28.80
+	Hs
		201495 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF16_HUMAN (29-195): 3.7e-63: 197: 26.59
+	Hs
		225920 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF17_HUMAN (46-226): 7.88e-62: 194: 63.24
+	Hs
		601114 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF7_HUMAN (54-195): 2.32e-59: 187: 28.08
+	Hs
		399135 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF1_HUMAN (74-194): 1.83e-48: 158: 23.58
+	Hs
		447025 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF2_HUMAN (72-195): 1.21e-46: 157: 29.84
+	Hs
		517734 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF5_HUMAN (70-209): 1.11e-44: 152: 26.85
+	Hs
		640029 PTX3_HUMAN (1-381): 0: 543: 100.00		FGF22_HUMAN (43-196): 5.38e-41: 139: 21.52
+	Hs
		320640 NPTX1_HUMAN (70-377): 1.05e-99: 304: 25.32		FGF19_HUMAN (68-226): 7.56e-41: 140: 18.79