HitPredict

Interactor 1: RADI (P26043)
Radixin (ESP10)
Gene: Rdx

Interactor 2: ICAM2 (P35330)
Intercellular adhesion molecule 2 (ICAM-2) (Lymphocyte function-associated AG-1 counter-receptor) (CD antigen CD102)
Gene: ICAM2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	16615918, 12554651
Identification Methods	surface plasmon resonance, x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005902 - microvillus GO:0032154 - cleavage furrow
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Mm			1 277
+	Hs
		530235 RADI_HUMAN (1-583): 3e-168: 492: 98.46		ICAM2_HUMAN (1-273): 9.04e-118: 340: 59.78
+	Hs
		530232 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		ICAM2_HUMAN (1-273): 9.04e-118: 340: 59.78
+	Hs
		530234 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		ICAM2_HUMAN (1-273): 9.04e-118: 340: 59.78
+	Hs
		547278 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		ICAM5_HUMAN (19-224): 2.12e-69: 232: 33.17
+	Hs
		546948 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		ICAM3_HUMAN (5-224): 1.47e-70: 228: 32.13
+	Mm
		530229 RADI_MOUSE (1-583): 2.49e-168: 492: 100.00		ICAM1_MOUSE (9-223): 1.4e-67: 220: 34.26
+	Hs
		640050 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		ICAM3_HUMAN (5-224): 1.47e-70: 228: 32.13
+	Hs
		399964 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		ICAM1_HUMAN (15-225): 5.11e-64: 211: 32.08
+	Hs
		399982 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		ICAM1_HUMAN (15-225): 5.11e-64: 211: 32.08
+	Mm
		640203 RADI_MOUSE (1-583): 2.49e-168: 492: 100.00		VCAM1_MOUSE (20-233): 2.6e-41: 153: 21.53
+	Hs
		546923 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		VCAM1_HUMAN (20-233): 1.55e-43: 159: 20.18
+	Hs
		663992 PTN4_HUMAN (4-483): 6.27e-130: 404: 23.40		ICAM5_HUMAN (19-224): 2.12e-69: 232: 33.17
+	Hs
		581442 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		VCAM1_HUMAN (20-233): 1.55e-43: 159: 20.18
+	Hs
		81626 B7Z5V2_HUMAN (1-583): 1.18e-140: 420: 71.84		VCAM1_HUMAN (20-233): 1.55e-43: 159: 20.18
+	Hs
		719746 RADI_HUMAN (1-583): 3e-168: 492: 98.46		KIRR3_HUMAN (20-223): 1.52e-13: 72.1: 13.58
+	Hs
		581462 PTN4_HUMAN (4-483): 6.27e-130: 404: 23.40		VCAM1_HUMAN (20-233): 1.55e-43: 159: 20.18
+	Hs
		547134 EZRI_HUMAN (1-583): 2.82e-165: 485: 76.28		KIRR3_HUMAN (20-223): 1.52e-13: 72.1: 13.58
+	Hs
		640132 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		TITIN_HUMAN (28-193): 1.24e-11: 66.7: 19.89
+	Hs
		719447 MERL_HUMAN (2-583): 3.58e-156: 462: 45.47		PGBM_HUMAN (26-254): 1.56e-09: 60.6: 17.48
+	Hs
		663990 PTN4_HUMAN (4-483): 6.27e-130: 404: 23.40		CADM1_HUMAN (26-224): 4.36e-16: 79.5: 16.20