HitPredict

Interactor 1: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 255
+	Hs
		663970 PTN4_HUMAN (1-913): 0: 804: 50.11		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910025 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910185 E41L3_HUMAN (21-661): 2.01e-121: 397: 24.11		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		204644 E41L2_HUMAN (19-550): 1.29e-117: 384: 24.06		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		505612 EPB41_HUMAN (7-534): 6.28e-117: 379: 24.39		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909498 PTN13_HUMAN (12-669): 6.96e-74: 268: 17.39		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909614 PTN21_HUMAN (25-320): 2.34e-30: 131: 29.26		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909595 PTN14_HUMAN (30-319): 3.46e-27: 121: 30.10		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00