HitPredict

Interactor 1: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Interactor 2: VANG1 (Q8TAA9)
Vang-like protein 1 (Loop-tail protein 2 homolog) (LPP2) (Strabismus 2) (Van Gogh-like protein 1)
Gene: VANGL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 524
+	Hs
		640288 PTN3_HUMAN (1-913): 0: 856: 100.00		VANG2_HUMAN (1-524): 0: 668: 72.05
+	Hs
		1250822 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		VANG1_HUMAN (1-524): 0: 822: 100.00
+	Hs
		1250828 E41L5_HUMAN (10-660): 1.1e-125: 398: 22.31		VANG1_HUMAN (1-524): 0: 822: 100.00
+	Hs
		1250850 E41L3_HUMAN (21-661): 2.01e-121: 397: 24.11		VANG1_HUMAN (1-524): 0: 822: 100.00
+	Hs
		1250829 E41LA_HUMAN (26-494): 3.57e-125: 395: 28.48		VANG1_HUMAN (1-524): 0: 822: 100.00
+	Hs
		1331059 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		VANG2_HUMAN (1-524): 0: 668: 72.05
+	Hs
		1356929 E41L3_HUMAN (21-661): 2.01e-121: 397: 24.11		VANG2_HUMAN (1-524): 0: 668: 72.05
+	Hs
		1336476 E41LA_HUMAN (26-494): 3.57e-125: 395: 28.48		VANG2_HUMAN (1-524): 0: 668: 72.05
+	Hs
		573812 PTN1_HUMAN (630-899): 1.4e-49: 183: 36.43		VANG1_HUMAN (1-524): 0: 822: 100.00
+	Hs
		573971 PTN1_HUMAN (630-899): 1.4e-49: 183: 36.43		VANG2_HUMAN (1-524): 0: 668: 72.05