HitPredict

Interactor 1: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Hs			1 245
+	Hs
		757538 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646694 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		757555 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Mm
		873099 DDX6_MOUSE (1-483): 1.77e-151: 442: 97.72		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		640404 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		640426 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		640335 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	At
		788599 RH20_ARATH (31-467): 3.73e-141: 416: 25.17		14333_ARATH (3-243): 8e-143: 401: 61.63
+	Hs
		133888 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		133969 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		757534 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		640336 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Mm
		873100 DDX6_MOUSE (1-483): 1.77e-151: 442: 97.72		1433F_MOUSE (2-242): 4.62e-106: 308: 71.43
+	Hs
		640443 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		640398 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		571326 DDX5_HUMAN (15-467): 1.7e-142: 423: 25.70		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		571384 DDX5_HUMAN (15-467): 1.7e-142: 423: 25.70		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		133992 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		133957 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	At
		783414 IF4A1_ARATH (98-464): 3.58e-87: 275: 40.11		14332_ARATH (3-243): 8.65e-144: 404: 61.22