HitPredict

Interactor 1: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 26777405, 29395067
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 5 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 483
Hs

1 466
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Zm
+ Zm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024