HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26065575
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1616 Hs			1 129
+	Xl
		420791 P79922_XENLA (126-1616): 0: 1502: 70.07		H2A1_XENLA (1-127): 7.27e-65: 194: 92.91
+	Xl
		945507 P79922_XENLA (126-1616): 0: 1502: 70.07		H2AX_XENLA (1-128): 8.9e-63: 189: 86.72
+	Hs
		1087035 PB1_HUMAN (42-1162): 0: 602: 15.37		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391768 PB1_HUMAN (42-1162): 0: 602: 15.37		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		555528 PB1_HUMAN (42-1162): 0: 602: 15.37		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Nc
		1113876 Q3Y3Z1_NEUCR (1040-1604): 1.28e-120: 416: 22.53		H2A_NEUCR (15-128): 1.66e-59: 181: 85.09
+	Hs
		555674 DNM3B_HUMAN (1130-1325): 2.44e-41: 167: 17.65		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555694 SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555711 DNM3A_HUMAN (1128-1326): 1.35e-36: 152: 17.87		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555503 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12