Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 21516116, 26641092, 32296183, 26264872, 35271311, 22365833, 25416956, 16189514, 28514442, 1388271, 33961781, 21988832, 8647433, unassigned1304, 21460037, 11551507
Identification Methods two hybrid, affinity chromatography technology, pull down, genetic interference, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach, two hybrid prey pooling approach, x-ray crystallography, two hybrid array and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~zf-CCCH
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0006397 - mRNA processing
and 3 others

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Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 475
Hs

1 240
+ At
+ Hs
+ Dm
+ Dm
+ Sp
+ Ce
+ Hs
+ Hs
+ Pf

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Last updated: 15 Jul 2024