HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	26641092, 35271311, 32960270
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000245 - spliceosomal complex assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 790
+	Hs
		998066 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998026 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998053 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998037 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		516479 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		NCBP1_HUMAN (1-790): 0: 1180: 100.00