HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 403
+	Hs
		1054383 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00
+	Hs
		1157398 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00
+	Hs
		1031365 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00
+	Hs
		516559 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		JMJD6_HUMAN (1-403): 1.19e-158: 454: 100.00
+	Hs
		1063299 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		HIF1N_HUMAN (15-320): 3.79e-64: 210: 16.08
+	Hs
		1020339 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		HIF1N_HUMAN (15-320): 3.79e-64: 210: 16.08
+	Sp
		293749 U2AF2_SCHPO (49-472): 6.44e-73: 240: 29.32		JHD1_SCHPO (2-332): 1.45e-51: 187: 14.37