HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26641092, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 2335
+	Hs
		1063231 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		1054384 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		1159327 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		516560 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		PRP8_HUMAN (1-2335): 0: 4632: 100.00