HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 1230
+	Hs
		1063248 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1077409 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1020285 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1054412 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		680463 TIA1_HUMAN (253-475): 5.63e-36: 138: 15.70		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		963543 TIAR_HUMAN (251-473): 6.95e-33: 130: 14.67		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1202170 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1031380 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		516581 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		268605 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Hs
		268723 SART3_HUMAN (10-377): 4.33e-86: 285: 22.52		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Hs
		268715 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Hs
		268893 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Dm
		1371244 Q9VYI0_DROME (242-468): 2.17e-30: 123: 19.43		Q9VN44_DROME (175-1181): 1.96e-27: 123: 11.69
+	Hs
		1054475 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		GCN1_HUMAN (8-396): 2.82e-11: 70.4: 12.69
+	Dm
		1097895 Q24474_DROME (40-235): 4.81e-14: 75.7: 11.06		Q8MSM3_DROME (292-1012): 3.31e-41: 166: 13.73
+	Dm
		1097896 Q24474_DROME (40-235): 4.81e-14: 75.7: 11.06		Q9VN44_DROME (175-1181): 1.96e-27: 123: 11.69