HitPredict

Interactor 1: U2AF2 (P26369)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SRSF3 (P84104)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Mm			1 164
+	Hs
		641807 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35
+	Hs
		641718 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		641736 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		266913 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		641756 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516364 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		641753 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		641920 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Mm
		641996 U2AF2_MOUSE (1-475): 1.22e-88: 280: 100.00		TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70
+	Hs
		641738 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22
+	Hs
		641754 U2AF2_HUMAN (1-475): 8.01e-89: 281: 99.79		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Hs
		951964 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		992769 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		266990 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		853892 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		1031328 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516518 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		1028546 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		993716 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22
+	Hs
		1028909 RBM39_HUMAN (145-471): 1.24e-48: 176: 18.23		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44