HitPredict

Interactor 1: UBP27 (A6NNY8)
Ubiquitin carboxyl-terminal hydrolase 27 (EC 3.4.19.12) (Deubiquitinating enzyme 27) (Ubiquitin carboxyl-terminal hydrolase 22-like) (Ubiquitin thioesterase 27) (Ubiquitin-specific-processing protease 27) (X-linked ubiquitin carboxyl-terminal hydrolase 27)
Gene: USP27X

Interactor 2: AT7L3 (Q14CW9)
Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog)
Gene: ATXN7L3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	24981860, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Sgf11~UCH
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 438 Hs			1 347
+	Hs
		1062121 UBP22_HUMAN (1-426): 2.45e-149: 436: 82.20		AT7L3_HUMAN (1-347): 0: 621: 100.00
+	Hs
		1062101 UBP51_HUMAN (1-426): 2.08e-140: 419: 73.77		AT7L3_HUMAN (1-347): 0: 621: 100.00
+	Dm
		1374838 NOT_DROME (2-426): 1.31e-111: 338: 51.24		SGF11_DROME (12-167): 1.37e-65: 207: 37.50
+	Hs
		1292919 UBP22_HUMAN (1-426): 2.45e-149: 436: 82.20		A7L3B_HUMAN (3-63): 1.98e-24: 97.1: 73.77