HitPredict

Interactor 1: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Interactor 2: GLCNE (Q9Y223)
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]
Gene: GNE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 169 Hs			1 722
+	Hs
		1216410 KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		889923 KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		889137 KR105_HUMAN (6-165): 3.51e-16: 75.5: 26.06		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		889030 KR103_HUMAN (22-166): 2.09e-16: 75.1: 26.12		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		991691 KRA11_HUMAN (31-167): 3.12e-15: 71.3: 30.44		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1309039 KR412_HUMAN (35-166): 1.04e-14: 70.1: 33.33		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		889727 KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317284 KRA92_HUMAN (47-166): 3.82e-14: 68.2: 34.71		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317309 KRA41_HUMAN (60-166): 8.69e-14: 66.7: 37.96		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317265 KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317305 KR411_HUMAN (1-131): 4.08e-12: 63.2: 25.19		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317330 KRA44_HUMAN (1-127): 4.34e-12: 62.4: 29.13		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		1317233 KRA98_HUMAN (52-167): 1.94e-11: 60.5: 35.04		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		889436 KR107_HUMAN (26-165): 1.87e-09: 57: 25.30		GLCNE_HUMAN (1-722): 0: 1030: 100.00
+	Hs
		888631 KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16		GLCNE_HUMAN (1-722): 0: 1030: 100.00