HitPredict

Interactor 1: RL13 (P26373)
Large ribosomal subunit protein eL13 (60S ribosomal protein L13) (Breast basic conserved protein 1)
Gene: RPL13

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	26167880, 33961781
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 688
+	Hs
		642534 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		SRPK1_HUMAN (27-688): 1.57e-125: 388: 53.22
+	Hs
		625123 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		CDK2_HUMAN (378-687): 1.93e-91: 288: 17.14
+	Hs
		642679 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		SRPK3_HUMAN (450-687): 1.19e-63: 223: 66.39
+	Hs
		642490 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		DYRK2_HUMAN (51-234): 1.48e-62: 221: 29.35
+	Sp
		251166 RL13_SCHPO (1-211): 3.98e-72: 219: 54.98		DSK1_SCHPO (437-686): 7.4e-74: 250: 44.40
+	Hs
		642343 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		CDK13_HUMAN (373-687): 1.6e-54: 204: 15.85
+	Hs
		642648 RL13_HUMAN (1-211): 3.37e-88: 260: 100.00		CDK12_HUMAN (291-687): 5.8e-54: 203: 13.17
+	Dm
		780925 RL13_DROME (5-210): 2.97e-81: 243: 62.32		Q9VR61_DROME (69-348): 1.39e-36: 149: 15.39