HitPredict

Interactor 1: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 216
+	Hs
		642738 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB8B_HUMAN (15-211): 6.32e-97: 282: 38.19
+	Hs
		642723 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18
+	Hs
		642743 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30
+	Hs
		592106 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		642722 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		642730 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		622608 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB8B_HUMAN (15-211): 6.32e-97: 282: 38.19
+	Hs
		622565 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		622577 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18
+	Hs
		592103 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		622572 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26
+	Hs
		622576 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		622590 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		642725 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB31_HUMAN (19-214): 2.77e-59: 186: 45.92
+	Hs
		642742 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB17_HUMAN (10-216): 1.19e-54: 175: 44.71
+	Hs
		642746 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB6B_HUMAN (16-213): 8.99e-53: 170: 41.71
+	Hs
		592626 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB6A_HUMAN (16-213): 2.31e-51: 166: 40.59
+	Hs
		622581 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB31_HUMAN (19-214): 2.77e-59: 186: 45.92
+	Hs
		622618 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB17_HUMAN (10-216): 1.19e-54: 175: 44.71
+	Hs
		592625 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB6A_HUMAN (16-213): 2.31e-51: 166: 40.59