HitPredict

Interactor 1: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Interactor 2: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26824392
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 207
+	Hs
		642720 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98
+	Hs
		642730 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		642723 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		642743 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96
+	Hs
		642738 RAE2_HUMAN (1-656): 0: 980: 100.00		RAB8B_HUMAN (1-207): 6.41e-86: 253: 82.61
+	Hs
		642722 RAE2_HUMAN (1-656): 0: 980: 100.00		RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06
+	Hs
		622573 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98
+	Hs
		622590 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		622577 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		622619 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96
+	Hs
		622570 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00
+	Hs
		622608 RAE1_HUMAN (1-652): 0: 946: 71.98		RAB8B_HUMAN (1-207): 6.41e-86: 253: 82.61
+	Hs
		622576 RAE1_HUMAN (1-652): 0: 946: 71.98		RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06
+	Hs
		678340 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98
+	Hs
		678333 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB13_HUMAN (1-206): 3.19e-89: 262: 61.17
+	Mm
		838709 GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49		RAB1A_MOUSE (1-204): 1.23e-87: 258: 54.41
+	Hs
		678344 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		678336 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00
+	Sc
		350882 GDI1_YEAST (176-597): 4.18e-144: 428: 23.72		YPT1_YEAST (1-204): 6.16e-81: 241: 49.03
+	Hs
		678343 GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49		RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06