Interactor 1: CNTF (P26441)
Ciliary neurotrophic factor (CNTF)
Gene: CNTF

Interactor 2: IL6RB (P40189)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: IL6ST

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 16051226
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005127 - ciliary neurotrophic factor receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008284 - positive regulation of cell population proliferation
GO:0042531 - positive regulation of tyrosine phosphorylation of STAT protein
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 200
Hs

1 918
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024