HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: CBLB (Q13191)
E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B)
Gene: CBLB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 982
+	Mm
		610551 HMGB2_MOUSE (1-187): 1.02e-41: 142: 98.40		CBL_MOUSE (25-976): 0: 674: 47.47
+	Hs
		449753 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		MCAF1_HUMAN (440-932): 1.82e-23: 109: 13.37
+	Hs
		727764 SOX5_HUMAN (20-169): 8.6e-30: 117: 23.33		MCAF1_HUMAN (440-932): 1.82e-23: 109: 13.37
+	Hs
		149943 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		NCAN_HUMAN (418-978): 1.12e-12: 74.7: 9.86
+	Hs
		818361 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		NSD1_HUMAN (373-939): 6.49e-27: 121: 13.23
+	Hs
		1243837 SOX7_HUMAN (3-90): 2.58e-23: 97.5: 23.86		KMT2C_HUMAN (387-931): 1.78e-14: 80.8: 11.98
+	Hs
		1243843 SOX17_HUMAN (6-90): 3.84e-23: 97.5: 22.35		KMT2C_HUMAN (387-931): 1.78e-14: 80.8: 11.98
+	Hs
		818266 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		KMT2C_HUMAN (387-931): 1.78e-14: 80.8: 11.98
+	Hs
		817913 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		MAP1A_HUMAN (461-918): 1.19e-10: 68.1: 12.23
+	Hs
		996722 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		ANR11_HUMAN (333-980): 1.47e-16: 87.4: 10.47
+	Rn
		94293 SOX9_RAT (4-87): 8.61e-15: 74: 17.86		F1M9G7_RAT (411-858): 1.97e-09: 64.2: 9.91