HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 209 Hs			1 325
+	Hs
		1032139 CIC_HUMAN (3-100): 1.66e-11: 64.7: 22.45		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		449632 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		643290 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		196970 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		903130 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		817868 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Ce
		1089274 SOX2_CAEEL (2-93): 4.44e-24: 97.8: 23.91		WDR51_CAEEL (177-325): 3.95e-36: 135: 18.00
+	Hs
		197008 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		903450 CIC_HUMAN (3-100): 1.66e-11: 64.7: 22.45		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		903169 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		1288324 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		996721 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72
+	Hs
		567746 UBF1_HUMAN (10-158): 1.47e-09: 58.9: 24.72		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		996824 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		818643 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		881823 SOX10_HUMAN (2-98): 5.81e-22: 94.4: 16.50		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		989556 SOX4_HUMAN (3-89): 1.9e-19: 87.4: 20.69		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		1281404 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		567741 UBF1_HUMAN (10-158): 1.47e-09: 58.9: 24.72		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		996813 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05