HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: LZTS1 (Q9Y250)
Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)
Gene: LZTS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	29721183
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 596
+	Hs
		818622 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		LZTS1_HUMAN (1-596): 1.46e-59: 210: 100.00
+	Hs
		818407 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		LZTS2_HUMAN (1-596): 1.2e-37: 150: 34.66
+	Hs
		989542 SOX4_HUMAN (3-89): 1.9e-19: 87.4: 20.69		TSC1_HUMAN (7-587): 1.97e-34: 141: 11.77
+	Hs
		643377 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		MY18A_HUMAN (240-536): 3.63e-11: 68.5: 12.58
+	Hs
		818141 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		MRCKA_HUMAN (329-595): 7.21e-19: 93.5: 18.28
+	Mm
		93555 SOX17_MOUSE (4-90): 2.02e-23: 98.2: 21.84		DESP_MOUSE (264-550): 2.28e-10: 66.1: 17.09
+	Hs
		551635 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		DESP_HUMAN (275-570): 1.97e-10: 66.5: 16.23
+	Hs
		725110 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		MYH10_HUMAN (140-534): 1.83e-10: 66.5: 11.62
+	Hs
		818070 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		PLEC_HUMAN (278-582): 2.47e-10: 66.1: 17.50
+	Hs
		551812 CIC_HUMAN (3-100): 1.66e-11: 64.7: 22.45		DESP_HUMAN (275-570): 1.97e-10: 66.5: 16.23