HitPredict

Interactor 1: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Interactor 2: RORA (P35398)
Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (RAR-related orphan receptor A) (Retinoid-related orphan receptor-alpha)
Gene: RORA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23208419
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 523
+	Hs
		643449 PTBP1_HUMAN (1-557): 1.59e-120: 368: 100.00		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Hs
		321016 PTBP3_HUMAN (1-557): 1.83e-101: 318: 74.01		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Hs
		369019 PTBP1_HUMAN (1-557): 1.59e-120: 368: 100.00		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		320942 PTBP3_HUMAN (1-557): 1.83e-101: 318: 74.01		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Dm
		983355 Q95UI6_DROME (13-557): 6.4e-79: 266: 49.74		FTF1B_DROME (23-488): 4.3e-83: 276: 19.23
+	Hs
		370088 HNRLL_HUMAN (44-556): 3.43e-96: 304: 25.91		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		516409 PABP1_HUMAN (3-375): 1.46e-44: 169: 13.58		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Hs
		823964 PABP4_HUMAN (3-378): 1.16e-43: 166: 10.62		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Hs
		446538 SNRPA_HUMAN (361-471): 6.95e-19: 89.1: 16.38		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Hs
		368886 PABP1_HUMAN (3-375): 1.46e-44: 169: 13.58		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		370422 PABP3_HUMAN (3-375): 4.05e-44: 167: 13.42		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		369534 PABP4_HUMAN (3-378): 1.16e-43: 166: 10.62		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		369739 PAP1L_HUMAN (3-380): 1.08e-42: 163: 11.86		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		540929 HNRPL_HUMAN (15-252): 9.17e-10: 63.4: 13.31		NR2C2_HUMAN (3-523): 3.96e-104: 326: 20.89
+	Mm
		509289 PABP1_MOUSE (3-375): 1.21e-44: 169: 13.58		RARA_MOUSE (8-147): 1.94e-52: 186: 43.97
+	Hs
		370797 RBM19_HUMAN (479-555): 3.4e-10: 65: 28.75		ESR1_HUMAN (1-514): 1.1e-68: 233: 18.42
+	Hs
		487896 HNRPL_HUMAN (15-252): 9.17e-10: 63.4: 13.31		RARA_HUMAN (8-147): 9.91e-53: 187: 44.68