HitPredict

Interactor 1: SYTC (P26639)
Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1)
Gene: TARS1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 768
+	Hs
		1042448 SYTM_HUMAN (45-723): 0: 833: 53.80		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		643747 SYTC_HUMAN (1-723): 0: 1008: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		430944 SYEP_HUMAN (303-720): 3.9e-125: 408: 18.59		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041895 SYPM_HUMAN (303-708): 7.64e-100: 317: 17.35		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042687 RM39_HUMAN (42-331): 8.3e-98: 306: 23.95		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		430943 SYEP_HUMAN (303-720): 3.9e-125: 408: 18.59		CUL1_HUMAN (18-768): 0: 707: 30.57