Interactor 1: SYVC (P26640)
Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)
Gene: VARS1

Interactor 2: SYLC (Q9P2J5)
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (cLRS)
Gene: LARS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27684187
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Anticodon_1~tRNA-synt_1, tRNA-synt_1~tRNA-synt_1
Common GO terms GO:0002161 - aminoacyl-tRNA editing activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006418 - tRNA aminoacylation for protein translation
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1264
Hs

1 1176
+ Hs
+ Sc
+ Ec
+ Zm
+ Hs
+ Hs

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Last updated: 15 Jul 2024