HitPredict

Interactor 1: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	17170118, 14688255, 11886850
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 246
+	Mm
		612137 TTP_MOUSE (1-326): 9.82e-60: 196: 83.79		1433B_MOUSE (1-246): 5.56e-141: 396: 98.78
+	Hs
		909474 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683291 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		926962 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		644227 TTP_HUMAN (1-326): 7.74e-64: 206: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		646828 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		815212 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683197 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		815222 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		644242 TTP_HUMAN (1-326): 7.74e-64: 206: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		904481 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		981948 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		646718 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		683988 TISB_HUMAN (25-326): 5.92e-52: 176: 30.20		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		815209 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		815235 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		683898 TISD_HUMAN (12-223): 1.19e-31: 125: 33.02		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62