HitPredict

Interactor 1: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Interactor 2: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	21078877, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening GO:0000932 - P-body GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 5 others more... GO:0005829 - cytosol GO:0030014 - CCR4-NOT complex GO:0046872 - metal ion binding GO:0060213 - positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:1900153 - positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	326
Hs

1	285

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024