Interactor 1: SOS (P26675)
Protein son of sevenless
Gene: SOS
Interactor 2: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.944 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9671493, 8462098, 22028469, 35952612, 9178769, unassigned4 |
| Identification Methods | affinity chromatography technology, far western blotting, unspecified method, solution state nmr, pull down, experimental interaction detection |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, RhoGEF~SH3_1 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0007265 - Ras protein signal transduction GO:0007426 - tracheal outgrowth, open tracheal system GO:0007427 - epithelial cell migration, open tracheal system and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
