HitPredict

Interactor 1: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Interactor 2: PMP22 (Q01453)
Peripheral myelin protein 22 (PMP-22) (Growth arrest-specific protein 3) (GAS-3)
Gene: PMP22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 160
+	Hs
		644551 NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00		EMP1_HUMAN (1-159): 8.52e-51: 161: 39.75
+	Hs
		644552 NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00		EMP3_HUMAN (20-160): 7.91e-49: 156: 42.07
+	Hs
		964830 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		PMP22_HUMAN (1-160): 8.79e-54: 168: 100.00
+	Hs
		426824 ASGR2_HUMAN (88-232): 1.08e-42: 148: 17.50		PMP22_HUMAN (1-160): 8.79e-54: 168: 100.00
+	Hs
		426819 ASGR2_HUMAN (88-232): 1.08e-42: 148: 17.50		EMP1_HUMAN (1-159): 8.52e-51: 161: 39.75
+	Hs
		964823 CD69_HUMAN (113-231): 5.43e-35: 125: 26.45		PMP22_HUMAN (1-160): 8.79e-54: 168: 100.00
+	Hs
		47313 CD209_HUMAN (96-231): 9.74e-41: 145: 21.77		A0A6Q8PF08_HUMAN (22-59): 2.64e-09: 55.7: 100.00