Interactor 1: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1
Interactor 2: KLRD1 (Q13241)
Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
Gene: KLRD1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.960 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8943374, 9034158, 10320637, 18448674, 18083576, 16237464, 32575403 |
| Identification Methods | affinity chromatography technology, surface plasmon resonance, x-ray crystallography, anti tag coimmunoprecipitation, blue native page |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Lectin_C~Lectin_C |
| Common GO terms | GO:0001915 - negative regulation of T cell mediated cytotoxicity GO:0002223 - stimulatory C-type lectin receptor signaling pathway GO:0002250 - adaptive immune response GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane and 9 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
