HitPredict

Interactor 1: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Interactor 2: PTPRU (Q92729)
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)
Gene: PTPRU

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	fn3~Lectin_C
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 1446
+	Hs
		1100775 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		PTPRU_HUMAN (1-1446): 0: 1131: 100.00
+	Hs
		1269186 CLC2D_HUMAN (51-231): 6.82e-43: 145: 21.28		PTPRU_HUMAN (1-1446): 0: 1131: 100.00
+	Hs
		1069991 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		PTPRK_HUMAN (26-1442): 0: 1098: 59.48
+	Hs
		489893 CSPG2_HUMAN (113-231): 4.2e-43: 157: 20.93		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		149944 NCAN_HUMAN (113-231): 1.17e-42: 155: 19.38		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		490037 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		59752 KLRG2_HUMAN (75-231): 3.26e-45: 157: 24.05		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32