HitPredict

Interactor 1: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Interactor 2: MRC2 (Q9UBG0)
C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280)
Gene: MRC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Lectin_C~fn2, Lectin_C~Lectin_C
Common GO terms	GO:0030246 - carbohydrate binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 1479
+	Hs
		530384 PGCB_HUMAN (12-233): 5.18e-51: 179: 18.64		CSPG2_HUMAN (879-1121): 7.22e-31: 135: 19.77
+	Hs
		991266 NKG2E_HUMAN (1-225): 2.84e-67: 209: 69.03		SE1L1_HUMAN (178-228): 4.38e-14: 79.7: 58.82
+	Mm
		1208639 C209B_MOUSE (10-231): 2.92e-51: 170: 16.80		C209B_MOUSE (951-1113): 1.14e-27: 117: 22.02
+	Hs
		59764 KLRG2_HUMAN (75-231): 3.26e-45: 157: 24.05		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		1329767 CLC4M_HUMAN (95-232): 4.96e-43: 151: 21.48		CLC4M_HUMAN (969-1117): 3.11e-32: 132: 24.68
+	Hs
		1329768 CLC4M_HUMAN (95-232): 4.96e-43: 151: 21.48		CD209_HUMAN (666-821): 6.64e-32: 131: 21.38
+	Hs
		1170205 CL17A_HUMAN (118-232): 3.67e-43: 151: 20.33		CL17A_HUMAN (663-812): 1.53e-29: 124: 23.33
+	Hs
		426840 CL17A_HUMAN (118-232): 3.67e-43: 151: 20.33		ASGR2_HUMAN (650-813): 3.09e-29: 121: 21.51
+	Hs
		426865 CLC7A_HUMAN (36-233): 4.75e-43: 147: 21.61		ASGR2_HUMAN (650-813): 3.09e-29: 121: 21.51
+	Dr
		60054 A4JYN2_DANRE (9-233): 9.63e-41: 150: 13.93		A4JYN2_DANRE (619-820): 1.12e-24: 114: 20.49
+	Hs
		530366 CSPG2_HUMAN (113-231): 4.2e-43: 157: 20.93		LYAM3_HUMAN (686-837): 2.62e-16: 86.8: 12.42
+	Hs
		439251 PGCB_HUMAN (12-233): 5.18e-51: 179: 18.64		MMP2_HUMAN (180-229): 1.58e-09: 64.7: 48.00
+	Hs
		530363 CSPG2_HUMAN (113-231): 4.2e-43: 157: 20.93		LYAM1_HUMAN (500-705): 6.7e-14: 77.2: 14.40
+	Hs
		1357138 CLC4E_HUMAN (51-231): 2.31e-43: 147: 16.51		CLC4E_HUMAN (1124-1234): 1e-15: 79.9: 20.00
+	Hs
		530364 CSPG2_HUMAN (113-231): 4.2e-43: 157: 20.93		MMP9_HUMAN (180-229): 4.9e-10: 66.2: 52.00
+	Hs
		540432 COL12_HUMAN (106-231): 4.95e-41: 150: 20.86		MMP9_HUMAN (180-229): 4.9e-10: 66.2: 52.00
+	Hs
		1263929 CLC4E_HUMAN (51-231): 2.31e-43: 147: 16.51		CLC4D_HUMAN (1270-1396): 8.73e-12: 68.3: 22.14
+	Hs
		439244 COL12_HUMAN (106-231): 4.95e-41: 150: 20.86		MMP2_HUMAN (180-229): 1.58e-09: 64.7: 48.00