HitPredict

Interactor 1: NKG2C (P26717)
NKG2-C type II integral membrane protein (CD159 antigen-like family member C) (NK cell receptor C) (NKG2-C-activating NK receptor) (CD antigen CD159c)
Gene: KLRC2

Interactor 2: GAS6 (Q14393)
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
Gene: GAS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 231 Hs			1 678
+	Hs
		644570 NKG2A_HUMAN (1-231): 1.4e-64: 201: 75.11		GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00
+	Hs
		1053503 CL12B_HUMAN (109-229): 1.28e-41: 144: 29.77		GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00
+	Hs
		1053534 CLC2D_HUMAN (71-229): 7.05e-41: 139: 22.98		GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00
+	Hs
		1020123 KLRB1_HUMAN (35-231): 1.12e-38: 135: 19.25		GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00
+	Hs
		1053506 CL12A_HUMAN (109-229): 3.69e-27: 106: 23.81		GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00
+	Hs
		957282 PGCB_HUMAN (12-231): 3.85e-54: 188: 17.95		FBLN2_HUMAN (158-287): 8.43e-13: 73.9: 36.88
+	Hs
		804301 CLC2B_HUMAN (80-231): 4.76e-40: 136: 23.38		NOTC1_HUMAN (8-310): 4.42e-25: 113: 17.58
+	Hs
		942485 CLC4M_HUMAN (2-230): 3.29e-55: 183: 15.98		CNTP1_HUMAN (478-672): 7.73e-10: 64.6: 13.71
+	Hs
		417469 FCER2_HUMAN (9-229): 4.61e-47: 159: 18.18		NOTC2_HUMAN (4-276): 4.25e-13: 75.3: 12.30
+	Hs
		530377 CSPG2_HUMAN (111-229): 7.51e-43: 156: 20.16		FBLN2_HUMAN (158-287): 8.43e-13: 73.9: 36.88
+	Hs
		530367 CSPG2_HUMAN (111-229): 7.51e-43: 156: 20.16		FBN1_HUMAN (118-227): 1.33e-09: 63.9: 33.33
+	Hs
		59754 KLRG2_HUMAN (108-229): 1.27e-41: 147: 23.58		LTBP1_HUMAN (58-262): 6.89e-10: 64.8: 19.27
+	Hs
		59747 KLRG2_HUMAN (108-229): 1.27e-41: 147: 23.58		CNTP1_HUMAN (478-672): 7.73e-10: 64.6: 13.71
+	Hs
		980478 CLC2B_HUMAN (80-231): 4.76e-40: 136: 23.38		NOTC2_HUMAN (4-276): 4.25e-13: 75.3: 12.30
+	Hs
		296667 CLC4D_HUMAN (53-228): 2.38e-39: 136: 16.83		SLIT2_HUMAN (78-200): 1.59e-10: 66.8: 19.84