HitPredict

Interactor 1: NKG2C (P26717)
NKG2-C type II integral membrane protein (CD159 antigen-like family member C) (NK cell receptor C) (NKG2-C-activating NK receptor) (CD antigen CD159c)
Gene: KLRC2

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 231 Hs			1 501
+	Hs
		1028537 KLRD1_HUMAN (69-231): 7.55e-43: 144: 31.98		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		1355536 CLC2D_HUMAN (71-229): 7.05e-41: 139: 22.98		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		1357142 CLC4E_HUMAN (47-229): 3.87e-40: 139: 14.71		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		1020153 KLRB1_HUMAN (35-231): 1.12e-38: 135: 19.25		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		966133 CLC4E_HUMAN (47-229): 3.87e-40: 139: 14.71		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		966094 CLC4D_HUMAN (53-228): 2.38e-39: 136: 16.83		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		1028512 KLRD1_HUMAN (69-231): 7.55e-43: 144: 31.98		CTR3_HUMAN (32-419): 2.23e-75: 250: 18.57
+	Hs
		1264252 CLC2D_HUMAN (71-229): 7.05e-41: 139: 22.98		CTR3_HUMAN (32-419): 2.23e-75: 250: 18.57
+	Hs
		1020138 KLRB1_HUMAN (35-231): 1.12e-38: 135: 19.25		CTR3_HUMAN (32-419): 2.23e-75: 250: 18.57
+	Hs
		217103 NKG2F_HUMAN (1-140): 3.54e-39: 134: 87.41		CTR3_HUMAN (32-419): 2.23e-75: 250: 18.57