HitPredict

Interactor 1: NKG2D (P26718)
NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)
Gene: KLRK1

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0030246 - carbohydrate binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 592
+	Hs
		654414 COL12_HUMAN (84-213): 8.39e-45: 160: 19.86		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654896 CLC4E_HUMAN (25-213): 8.57e-42: 142: 19.90		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		644666 NKG2C_HUMAN (22-215): 9.17e-41: 140: 20.71		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		644539 NKG2A_HUMAN (22-215): 1.77e-40: 139: 22.56		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		426768 ASGR1_HUMAN (66-215): 4.24e-39: 137: 22.70		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654453 CLC4G_HUMAN (80-214): 7.27e-37: 132: 24.14		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654301 KLRD1_HUMAN (57-216): 5.29e-38: 131: 27.65		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654610 CLC2B_HUMAN (57-214): 2.87e-37: 128: 27.50		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654883 CLC2D_HUMAN (58-216): 1.72e-36: 128: 28.57		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161082 COL12_HUMAN (84-213): 8.39e-45: 160: 19.86		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161168 CLC4E_HUMAN (25-213): 8.57e-42: 142: 19.90		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161020 NKG2C_HUMAN (22-215): 9.17e-41: 140: 20.71		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161019 NKG2A_HUMAN (22-215): 1.77e-40: 139: 22.56		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161124 CLC4D_HUMAN (42-212): 2.19e-39: 136: 16.75		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161060 KLRD1_HUMAN (57-216): 5.29e-38: 131: 27.65		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161125 CLC2B_HUMAN (57-214): 2.87e-37: 128: 27.50		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161059 KLRB1_HUMAN (58-215): 1.39e-26: 103: 24.10		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653770 CLC4E_HUMAN (25-213): 8.57e-42: 142: 19.90		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		644538 NKG2A_HUMAN (22-215): 1.77e-40: 139: 22.56		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		653675 CLC4D_HUMAN (42-212): 2.19e-39: 136: 16.75		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33