Interactor 1: RFA2 (P26754)
Replication factor A protein 2 (RF-A protein 2) (DNA-binding protein BUF1) (Replication protein A 36 kDa subunit)
Gene: RFA2

Interactor 2: ATR (P38111)
Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1)
Gene: MEC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.755

The method score is based on:

Property Details
Experiments 16148046, 37968396, 14642562, 12967660, 16118184, 31369547, 18922789, 20489023, 23355394
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0006260 - DNA replication
GO:0006281 - DNA repair
GO:0007131 - reciprocal meiotic recombination
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 273
Sc

1 2368
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024