HitPredict

Interactor 1: CD27 (P26842)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Interactor 2: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.50	0.669

Property	Details
Experiments	26186194, 28514442, 9794406, 9582383, 33961781, 9692890
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 Hs			1 501
+	Mm
		761802 CD27_MOUSE (1-260): 5.03e-66: 207: 64.23		TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83
+	Hs
		639576 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00
+	Mm
		648951 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83
+	Mm
		761824 TNR14_MOUSE (9-250): 4.75e-49: 164: 17.32		TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83
+	Mm
		192583 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF2_MOUSE (1-501): 9.33e-158: 459: 86.83
+	Hs
		584390 TNR1A_HUMAN (27-260): 1.96e-40: 146: 20.49		TRAF2_HUMAN (1-501): 2.31e-159: 463: 100.00
+	Hs
		129533 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90
+	Hs
		645797 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF3_HUMAN (14-501): 2.21e-112: 345: 31.31
+	Hs
		129532 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF5_HUMAN (7-501): 1.93e-115: 353: 30.90
+	Mm
		648958 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF3_MOUSE (9-501): 1.15e-113: 348: 31.75
+	Hs
		639578 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF3_HUMAN (14-501): 2.21e-112: 345: 31.31
+	Mm
		648955 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87
+	Hs
		639668 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF6_HUMAN (2-498): 5.24e-109: 335: 27.08
+	Mm
		936208 TNR14_MOUSE (9-250): 4.75e-49: 164: 17.32		TRAF5_MOUSE (7-501): 8.51e-114: 348: 29.25
+	Mm
		192584 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF5_MOUSE (7-501): 8.51e-114: 348: 29.25
+	Mm
		192587 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF3_MOUSE (9-501): 1.15e-113: 348: 31.75
+	Hs
		645796 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF1_HUMAN (130-499): 1.15e-88: 279: 37.44
+	Mm
		192585 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF6_MOUSE (2-498): 2.51e-110: 339: 27.87
+	Hs
		639638 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF4_HUMAN (17-498): 1.52e-94: 296: 29.12
+	Hs
		639577 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF1_HUMAN (130-499): 1.15e-88: 279: 37.44