HitPredict

Interactor 1: CD27 (P26842)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Interactor 2: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	9794406, 9582383
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 Hs			1 568
+	Hs
		639578 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00
+	Mm
		648958 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13
+	Mm
		192587 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13
+	Hs
		129533 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79
+	Hs
		129532 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79
+	Hs
		645795 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Mm
		936208 TNR14_MOUSE (9-250): 4.75e-49: 164: 17.32		TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36
+	Mm
		192584 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36
+	Mm
		761802 CD27_MOUSE (1-260): 5.03e-66: 207: 64.23		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Hs
		639576 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Mm
		648951 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Mm
		761824 TNR14_MOUSE (9-250): 4.75e-49: 164: 17.32		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Mm
		192583 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Hs
		645796 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		TRAF1_HUMAN (151-563): 2.25e-80: 260: 32.63
+	Hs
		584390 TNR1A_HUMAN (27-260): 1.96e-40: 146: 20.49		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Mm
		648955 TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77		TRAF6_MOUSE (20-562): 1.2e-84: 275: 20.48
+	Hs
		639668 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF6_HUMAN (22-562): 7.2e-84: 272: 21.28
+	Hs
		639577 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF1_HUMAN (151-563): 2.25e-80: 260: 32.63
+	Hs
		639638 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		TRAF4_HUMAN (37-562): 2.06e-77: 254: 23.15
+	Mm
		192585 TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00		TRAF6_MOUSE (20-562): 1.2e-84: 275: 20.48