HitPredict

Interactor 1: CD27 (P26842)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Interactor 2: AT2B3 (Q16720)
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Gene: ATP2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 1220
+	Hs
		588541 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		AT2B1_HUMAN (1-1220): 0: 1207: 78.94
+	Hs
		619289 TNR27_HUMAN (26-256): 5.03e-33: 123: 22.27		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		645813 CD27_HUMAN (1-260): 1.02e-74: 229: 100.00		AT2A3_HUMAN (51-1061): 0: 773: 25.28
+	Hs
		639624 TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52		AT2A3_HUMAN (51-1061): 0: 773: 25.28
+	Hs
		163746 TNR1B_HUMAN (13-174): 1.53e-36: 136: 19.77		AT2A1_HUMAN (51-1072): 0: 799: 24.27
+	Hs
		393028 TNR1A_HUMAN (27-260): 1.96e-40: 146: 20.49		AT1A1_HUMAN (13-1073): 0: 751: 21.63
+	Hs
		561496 TNR1A_HUMAN (27-260): 1.96e-40: 146: 20.49		AT2A2_HUMAN (50-1075): 0: 750: 24.20
+	Hs
		393030 TNR1B_HUMAN (13-174): 1.53e-36: 136: 19.77		AT1A1_HUMAN (13-1073): 0: 751: 21.63
+	Hs
		561497 TNR1B_HUMAN (13-174): 1.53e-36: 136: 19.77		AT2A2_HUMAN (50-1075): 0: 750: 24.20
+	Hs
		530873 TNR9_HUMAN (40-183): 6.75e-21: 90.3: 20.00		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		155882 TR10C_HUMAN (42-142): 1.98e-15: 75.6: 18.87		AT1A3_HUMAN (39-1073): 0: 756: 23.47