HitPredict

Interactor 1: IL3RA (P26951)
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)
Gene: IL3RA

Interactor 2: CISH (Q9NSE2)
Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)
Gene: CISH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	7796808
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 258
+	Hs
		412028 IL3RA_HUMAN (18-378): 7.15e-106: 317: 100.00		FYN_HUMAN (39-248): 8.37e-42: 151: 13.06
+	Hs
		560479 PRLR_HUMAN (101-353): 2.02e-58: 201: 16.79		CISH_HUMAN (1-258): 2.61e-67: 210: 100.00
+	Hs
		146590 PRLR_HUMAN (101-353): 2.02e-58: 201: 16.79		SOCS2_HUMAN (45-258): 1.84e-53: 173: 37.85
+	Rn
		70070 GHR_RAT (94-347): 8.85e-42: 156: 15.49		B1WBX9_RAT (1-258): 3.95e-68: 212: 90.31
+	Hs
		500974 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		CISH_HUMAN (1-258): 2.61e-67: 210: 100.00
+	Hs
		147385 PRLR_HUMAN (101-353): 2.02e-58: 201: 16.79		SOCS3_HUMAN (44-254): 6.27e-48: 160: 32.42
+	Hs
		146586 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		SOCS2_HUMAN (45-258): 1.84e-53: 173: 37.85
+	Hs
		548790 CSF2R_HUMAN (3-372): 3.94e-72: 232: 29.29		P85A_HUMAN (52-188): 2.6e-21: 94.5: 16.06
+	Hs
		147382 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		SOCS3_HUMAN (44-254): 6.27e-48: 160: 32.42
+	Hs
		560475 PRLR_HUMAN (101-353): 2.02e-58: 201: 16.79		PTN11_HUMAN (77-222): 6.35e-26: 107: 19.46
+	Hs
		181779 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		SOCS1_HUMAN (55-258): 2e-42: 145: 28.16
+	Mm
		562609 GHR_MOUSE (78-347): 5.69e-42: 157: 14.97		PTN11_MOUSE (77-222): 7.34e-26: 107: 19.46
+	Hs
		500960 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		PTN11_HUMAN (77-222): 6.35e-26: 107: 19.46
+	Hs
		985961 EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50		PTN11_HUMAN (77-222): 6.35e-26: 107: 19.46
+	Hs
		500948 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		P85A_HUMAN (52-188): 2.6e-21: 94.5: 16.06
+	Mm
		643058 IL2RG_MOUSE (93-368): 1.93e-43: 156: 17.93		P85A_MOUSE (52-188): 4.14e-21: 94.1: 16.06
+	Hs
		129180 GHR_HUMAN (89-347): 8.09e-42: 156: 14.78		P85B_HUMAN (52-183): 6.6e-21: 93.4: 17.42
+	Hs
		655380 EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50		P85A_HUMAN (52-188): 2.6e-21: 94.5: 16.06
+	Hs
		129297 EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50		P85B_HUMAN (52-183): 6.6e-21: 93.4: 17.42
+	Hs
		433772 EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50		LYN_HUMAN (41-209): 8.26e-18: 84.2: 19.21