Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23967299
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~Activin_recp, Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0007178 - cell surface receptor protein serine/threonine kinase signaling pathway
GO:0009952 - anterior/posterior pattern specification
GO:0009986 - cell surface
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 513
Hs

1 1038
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024