Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A
Interactor 2: NODAL (Q96S42)
Nodal homolog
Gene: NODAL
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28126904 |
Identification Methods | pull down |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Activin_recp~TGF_beta |
Common GO terms | GO:0032927 - positive regulation of activin receptor signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060391 - positive regulation of SMAD protein signal transduction |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024