HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 189
+	Hs
		64708 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		349384 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		895065 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97
+	Hs
		1070234 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		349370 RHG29_HUMAN (134-911): 5.44e-66: 249: 11.78		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		49624 RHG10_HUMAN (126-752): 1.62e-67: 247: 15.18		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		349280 ABR_HUMAN (350-569): 2.79e-66: 245: 32.89		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		253300 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		348636 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		RASN_HUMAN (1-189): 2.37e-85: 251: 85.19
+	Hs
		350234 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		350325 RHG12_HUMAN (312-568): 5.13e-71: 259: 28.68		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		895119 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97
+	Hs
		993020 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		350113 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		895053 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97
+	Hs
		350207 RHG31_HUMAN (358-1637): 5.78e-63: 240: 21.26		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		350086 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		914029 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88
+	Rn
		1157320 R9PXS2_RAT (128-552): 5.73e-63: 235: 13.48		RAB1A_RAT (4-187): 7.4e-74: 222: 34.36
+	Rn
		896707 R9PXS2_RAT (128-552): 5.73e-63: 235: 13.48		RAB14_RAT (4-184): 3.77e-72: 218: 29.51