HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 512
+	Hs
		64641 RHG32_HUMAN (1-2087): 0: 1424: 100.00		LCK_HUMAN (1-512): 0: 582: 63.62
+	Hs
		64648 RHG32_HUMAN (1-2087): 0: 1424: 100.00		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		64642 RHG32_HUMAN (1-2087): 0: 1424: 100.00		FYN_HUMAN (1-510): 0: 576: 54.12
+	Mm
		763398 RHG33_MOUSE (73-1289): 3.48e-114: 398: 30.65		FYN_MOUSE (1-510): 0: 576: 53.93
+	Hs
		147859 RHG33_HUMAN (74-1276): 2.2e-113: 395: 30.98		FYN_HUMAN (1-510): 0: 576: 54.12
+	Hs
		433814 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		LYN_HUMAN (1-512): 0: 611: 100.00
+	Hs
		433879 RHG12_HUMAN (312-568): 5.13e-71: 259: 28.68		LYN_HUMAN (1-512): 0: 611: 100.00
+	Hs
		411755 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		LCK_HUMAN (1-512): 0: 582: 63.62
+	Hs
		411763 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		LCK_HUMAN (1-512): 0: 582: 63.62
+	Hs
		523026 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		442896 3BP1_HUMAN (368-686): 4.12e-64: 235: 25.94		HCK_HUMAN (1-512): 0: 595: 70.70
+	Hs
		522938 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		411678 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		LCK_HUMAN (1-512): 0: 582: 63.62
+	Hs
		523225 3BP1_HUMAN (368-686): 4.12e-64: 235: 25.94		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		337492 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88
+	Ce
		220207 TG325_CAEEL (321-566): 1.2e-63: 236: 29.04		SRC2_CAEEL (1-510): 0: 530: 45.74
+	Hs
		337453 ABR_HUMAN (350-569): 2.79e-66: 245: 32.89		ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88
+	Hs
		337603 3BP1_HUMAN (368-686): 4.12e-64: 235: 25.94		ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88
+	Mm
		337622 3BP1_MOUSE (336-657): 1.78e-63: 233: 24.85		ABL1_MOUSE (32-509): 5.71e-172: 516: 37.88
+	Hs
		986382 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		BTK_HUMAN (2-505): 1.48e-156: 462: 33.86