HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MPIP2 (P30305)
M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)
Gene: CDC25B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	26496610, 33961781, 10713667, 15629715, 28514442
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 580
+	Rn
		823141 1433E_RAT (2-243): 1.31e-144: 406: 63.53		MPIP2_RAT (1-580): 0: 830: 79.66
+	Hs
		673463 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP2_HUMAN (1-580): 0: 823: 100.00
+	Hs
		673464 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP2_HUMAN (1-580): 0: 823: 100.00
+	Hs
		673452 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP2_HUMAN (1-580): 0: 823: 100.00
+	Mm
		673543 1433B_MOUSE (1-242): 2.84e-124: 354: 80.99		MPIP2_MOUSE (1-580): 0: 833: 80.90
+	Hs
		673453 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP2_HUMAN (1-580): 0: 823: 100.00
+	Hs
		673381 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP1_HUMAN (46-578): 0: 636: 44.73
+	Hs
		646655 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MPIP1_HUMAN (46-578): 0: 636: 44.73
+	Hs
		673382 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP1_HUMAN (46-578): 0: 636: 44.73
+	Hs
		673365 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP1_HUMAN (46-578): 0: 636: 44.73
+	Rn
		823139 1433E_RAT (2-243): 1.31e-144: 406: 63.53		MPIP1_RAT (45-578): 0: 618: 42.59
+	Hs
		673366 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP1_HUMAN (46-578): 0: 636: 44.73
+	Xl
		223343 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		MPIP2_XENLA (49-577): 0: 536: 35.53
+	Hs
		673560 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10
+	Hs
		646657 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10
+	Hs
		673562 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10
+	Hs
		673545 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10
+	Hs
		673546 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10
+	Rn
		89019 1433E_RAT (2-243): 1.31e-144: 406: 63.53		D4ADT2_RAT (65-577): 4.62e-108: 333: 31.75
+	Mm
		823143 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MPIP3_MOUSE (205-577): 2.24e-103: 321: 33.65