Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 12819203, 12454018, 31980649, 35044719, unassigned2173
Identification Methods affinity chromatography technology, pull down, unspecified method, anti tag coimmunoprecipitation, phage display
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_2~SH3_9
Common GO terms GO:0005829 - cytosol
GO:0015629 - actin cytoskeleton
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2087
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024