HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.762

Property	Details
Experiments	12535517, 33961781, 35271311, 36931259, 15161933, 24366813, 25796446, 27684187, 31501420, 31619268, 38280479, 22863277, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 504
+	Hs
		125318 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125169 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		647191 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		909930 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Mm
		910302 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73
+	Rn
		910358 1433E_RAT (2-243): 1.31e-144: 406: 63.53		NEDD4_RAT (28-504): 4.86e-116: 364: 16.77
+	Mm
		93264 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11
+	Mm
		808343 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98
+	Hs
		808460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		647201 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		808077 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		646713 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		910005 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Mm
		910339 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		WWTR1_MOUSE (39-504): 9.89e-56: 193: 38.90
+	At
		788566 14333_ARATH (3-243): 8e-143: 401: 61.63		UPL2_ARATH (216-504): 2.03e-50: 187: 10.47
+	Dm
		955002 1433E_DROME (2-242): 6.77e-143: 401: 65.02		YAP1_DROME (52-268): 1.16e-44: 163: 29.25
+	Hs
		909790 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		909674 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18
+	Hs
		647091 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		646997 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18